Narcan Impact and Managing Potential Adverse Reactions
Narcan, a lifesaving drug used to reverse opioid overdoses, became available over the counter (OTC) in U.S. pharmacies starting in 2023 [1][2][4]. However, studies from 2024-2025 show that accessibility can still be a challenge [2][3].
While most pharmacies have Narcan available, fewer than 20% stock it openly on shelves. Many pharmacies charge high prices, and signage indicating availability is often lacking [2]. Chain pharmacies have higher accessibility than independent ones, but barriers remain, including pharmacist training and store policies [2].
It's essential to note that Narcan may cause side effects, such as headache, and in some cases, an allergic reaction [3]. If you have a history of heart disease or have experienced a heart attack, you may be at a higher risk of heart problems from Narcan [1]. Symptoms of an allergic reaction can include rash, itching, flushing, swelling, and swelling of the mouth, tongue, or throat [3].
Opioid withdrawal symptoms after Narcan use can include abdominal pain, aggression or agitation, fever, goosebumps, increased heart rate, runny nose, sweating, trembling, and multiple occurrences after an opioid overdose [3]. If you experience symptoms of opioid withdrawal after receiving Narcan, emergency medical personnel should be called [3].
The risks of using Narcan while pregnant or breastfeeding aren't entirely known. However, the benefits of treating an opioid overdose during pregnancy or breastfeeding outweigh the risks [1]. If you have questions about using Narcan while pregnant or breastfeeding, talk with your doctor about the benefits and risks of using the drug [1].
It's also worth mentioning that Narcan won't reverse an alcohol overdose [3]. Interactions between Narcan and alcohol weren't reported in clinical studies [3].
In summary, while Narcan is OTC at pharmacies as of 2023, full over-the-counter accessibility is still uneven and improving gradually with ongoing efforts. If you have any heart conditions or have experienced an allergic reaction to Narcan or its ingredients, you should talk with your doctor about whether it's safe to use the drug [3]. Over-the-counter pain relievers such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil) can help with headache caused by Narcan [3].
[1] FDA approval of Narcan nasal spray for OTC use: https://www.fda.gov/news-events/press-announcements/fda-approves-first-over-counter-naloxone-nasal-spray-reverse-opioid-overdose
[2] Accessibility of Narcan in pharmacies: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168871/
[3] Narcan side effects and interactions: https://www.mayoclinic.org/drugs-supplements/naloxone-oral-route/side-effects/drg-20075669
[4] Narcan availability in pharmacies: https://www.cdc.gov/drugoverdose/prevention/know-narcan.html
- In health-and-wellness discussions, it's important to acknowledge that Narcan, though available over the counter from 2023, faces challenges in terms of even distribution in pharmacies.
2.Chain pharmacies can provide better access to Narcan compared to independent ones, but despite this, barriers such as pharmacist training and store policies remain.
- Side effects of Narcan may include headaches, allergic reactions, and possibly heart problems for those with a heart disease history or heart attack experience.
- Mental-health care professionals should be consulted regarding the use of Narcan, especially for individuals who have experienced allergic reactions to the drug or its components.
