Kyprolis Impact on Health: Frequent, Moderate, and Severe Side Effects
Kyprolis (carfilzomib) is a prescription medication approved by the Food and Drug Administration (FDA) to treat multiple myeloma in adults. The active ingredient in Kyprolis is carfilzomib, which belongs to the drug class of proteasome inhibitors.
While Kyprolis is effective in treating multiple myeloma, it's essential to be aware of its potential side effects and precautions.
Potential Side Effects
Kyprolis can cause a range of side effects, some of which may be mild and manageable, while others can be severe. Common side effects include fatigue, fever, diarrhea, headache, cough, insomnia, and upper respiratory infection.
More serious side effects include increased blood pressure, anemia, low level of platelets, blood clots, difficulty breathing, pulmonary hypertension, kidney problems, tumor lysis syndrome, bleeding, lung problems, progressive multifocal leukoencephalopathy, posterior reversible encephalopathy syndrome, thrombotic microangiopathy, cardiac problems, and liver problems.
Infusion-Related Reactions
Infusion-related reactions may occur with Kyprolis. Symptoms can include fever, joint or muscle pain, swelling or flushing of your face, vomiting, shortness of breath, low blood pressure, chest pain or tightness. In case of mild symptoms of an allergic reaction, it's important to call your doctor right away. For more serious reactions, seek immediate medical attention by calling 911 or your local emergency number.
Precautions and Management
Before receiving a Kyprolis infusion, your doctor will recommend taking a steroid medication called Hemady (dexamethasone) to help prevent more serious infusion-related reactions. To help prevent some side effects from Kyprolis, such as headache or fatigue, drinking more water each day may be beneficial.
Your doctor will also check your blood levels throughout your treatment with Kyprolis to monitor your liver. If you develop a URI during your treatment, tell your doctor. They may recommend medication, such as an antibiotic, to treat your infection.
During treatment with Kyprolis, your doctor will monitor you for heart problems and may monitor you more often if you're at increased risk for cardiac problems. If you have any symptoms of heart problems while receiving Kyprolis, talk with your doctor right away.
Pregnancy and Breastfeeding
If you're pregnant or planning to become pregnant, talk with your doctor. The same goes if you're breastfeeding or considering it. They can advise you on whether Kyprolis is right for you.
Conclusion
While Kyprolis is a valuable treatment option for multiple myeloma, it's crucial to be aware of its potential side effects and precautions. Ongoing vigilance and management by healthcare providers are essential for patients receiving Kyprolis. The FDA continues to monitor long-term safety closely, including serious adverse events that may emerge with extended use. Continued follow-up studies are important to fully understand the long-term safety profile of Kyprolis.
- Other heart diseases, cancer, and various medical conditions can be exacerbated by Kyprolis, making it crucial for patients with such health-and-wellness issues to inform their doctors before starting treatment.
- Owing to the science behind proteasome inhibitors, Kyprolis may cause a range of side effects, from common ones like fatigue and diarrhea to severe ones like blood clots and liver problems.
- During treatment with Kyprolis, it's essential to manage other heart diseases, as the medication may potentially cause cardiac problems, and close monitoring is necessary for increased risk patients.
